Abstract: Cephalotaxus mannii Hook. f. is a raw material resources of new medicine used for anti-cancer (leukaemia), which was found in 1970's in China. The natural resources of the plant is now being less and less. Protecting and establishing this raw medicinal resources base become more and more important. An investigation on the early growth performance of a 14-year-old plantation of C. mannii under un-extensive management was carried out at Jianfengling Forest Region, Hainan Province of China. It was showed that the mean annual increment (m.a.i.) was 0.42 cm in DBH, 0.39 m in tree height, 0.72m3 in volume (o.b.v.) and the total aboveground biomass (TAGB) was 7.678t/ha, the net production (excluding tree litter) was 0.548 t/ha/a with 833 individuals per ha in tree density. Although the stand productivity was low, the economic value of the medicine was high up to 800 thousand Yuan(RMB) per ha according to the harringtonine and homo-harringtonine in the bark biomass and their market price in 1989. Finally, the cultivating prospect of C. mannii also been discussed in this paper.