Effects of Sabina chinensis Volatiles on Spontaneous Behavior and Some Physiologic and Biochemical Indicators of Mice

ZHUO Pan; LIU Jin-juan; LI Xiao-chu; WANG Qi-qi; LI Chang-gen; JIANG Ji-hong

The effects of volatiles from branch and leaf of Sabina chinensis on open-field behaviors and the physiological and biochemical parameters of Kunming mice and the relationship between the volatiles and the environment conditions were investigated and evaluated. The results showed that distance in central grid, total distance and the time of movement had dose-dependent relationship. The behavior index of low-dose group was higher than that of the control while the behavior index of high-dose group was lower than that of the control group. It suggested that low concentration of volatile matter can improve the excitability of mice, and higher concentration would cause the mice showing inhibiting activity. The weight of all the mice showed a steady growth trend, indicating there was no effect on the appetite of mice. The physiological indicators of mice were normal, while the biochemical indicators of apolipoprotein A was significant different from the control group. The mechanism needs further exploration.

1. Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, Jiangsu Normal University, Xuzhou 221116, Jiangsu, China

Received Date: 2014-06-15

Abstract: The effects of volatiles from branch and leaf of Sabina chinensis on open-field behaviors and the physiological and biochemical parameters of Kunming mice and the relationship between the volatiles and the environment conditions were investigated and evaluated. The results showed that distance in central grid, total distance and the time of movement had dose-dependent relationship. The behavior index of low-dose group was higher than that of the control while the behavior index of high-dose group was lower than that of the control group. It suggested that low concentration of volatile matter can improve the excitability of mice, and higher concentration would cause the mice showing inhibiting activity. The weight of all the mice showed a steady growth trend, indicating there was no effect on the appetite of mice. The physiological indicators of mice were normal, while the biochemical indicators of apolipoprotein A was significant different from the control group. The mechanism needs further exploration.

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Reference (18)

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Effects of Sabina chinensis Volatiles on Spontaneous Behavior and Some Physiologic and Biochemical Indicators of Mice

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通讯作者: 陈斌, bchen63@163.com

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